FOG14118
EOG8GB5R1

sce:GPI8

Genes: 33

SGD Description
ER membrane glycoprotein subunit of the GPI transamidase complex; adds glycosylphosphatidylinositol (GPI) anchors to newly synthesized proteins; human PIG-K protein is a functional homolog


PomBase Description
pig-K


AspGD Description
Ortholog(s) have GPI-anchor transamidase activity, role in attachment of GPI anchor to protein and GPI-anchor transamidase complex localization


References

Benghezal M, et al. (1996 Dec 2). Yeast Gpi8p is essential for GPI anchor attachment onto proteins.

Meyer U, et al. (2000 Mar 28). Active site determination of Gpi8p, a caspase-related enzyme required for glycosylphosphatidylinositol anchor addition to proteins.

Ohishi K, et al. (2000 May). Gaa1p and gpi8p are components of a glycosylphosphatidylinositol (GPI) transamidase that mediates attachment of GPI to proteins.

Shams-Eldin H, et al. (2001 Jan 15). The Schizosaccharomyces pombe GPI8 gene complements a Saccharomyces cerevisiae GPI8 anchoring mutant.

Fraering P, et al. (2001 Oct). The GPI transamidase complex of Saccharomyces cerevisiae contains Gaa1p, Gpi8p, and Gpi16p.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 24 genes with posterior transmembrane prediction > 50%