FOG14077
EOG8GF1ZZ

sce:VPS28

Genes: 33

SGD Description
Component of the ESCRT-I complex; complex is involved in ubiquitin-dependent sorting of proteins into the endosome; conserved C-terminal domain interacts with ESCRT-III subunit Vps20p; other members include Stp22p, Srn2p, Vps28p, and Mvb12p


PomBase Description
ESCRT I complex subunit Vps28


AspGD Description
Ortholog(s) have protein complex binding activity


References

Rieder SE, et al. (1996 Jun). Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant.

Katzmann DJ, et al. (2003 Aug 4). Vps27 recruits ESCRT machinery to endosomes during MVB sorting.

Kostelansky MS, et al. (2006 Apr 7). Structural and functional organization of the ESCRT-I trafficking complex.

Teo H, et al. (2006 Apr 7). ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes.

Pineda-Molina E, et al. (2006 Aug). The crystal structure of the C-terminal domain of Vps28 reveals a conserved surface required for Vps20 recruitment.

Gill DJ, et al. (2007 Jan 24). Structural insight into the ESCRT-I/-II link and its role in MVB trafficking.

Kostelansky MS, et al. (2007 May 4). Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%