FOG13960
EOG8GQNN5

sce:MDM20

Genes: 29

SGD Description
Non-catalytic subunit of the NatB N-terminal acetyltransferase; NatB catalyzes N-acetylation of proteins with specific N-terminal sequences; involved in mitochondrial inheritance and actin assembly


PomBase Description
NatB N-acetyltransferase complex regulatory subunit Naa25


AspGD Description
Ortholog(s) have N-terminal protein N-methyltransferase activity, role in N-terminal peptidyl-methionine acetylation, regulation of mitotic actomyosin contractile ring assembly and cytosol localization


References

Hermann GJ, et al. (1997 Apr 7). The yeast gene, MDM20, is necessary for mitochondrial inheritance and organization of the actin cytoskeleton.

Polevoda B, et al. (2003 Aug 15). Nat3p and Mdm20p are required for function of yeast NatB Nalpha-terminal acetyltransferase and of actin and tropomyosin.

Singer JM, et al. (2003 Jun 24). Mdm20 protein functions with Nat3 protein to acetylate Tpm1 protein and regulate tropomyosin-actin interactions in budding yeast.

Coulton AT, et al. (2010 Oct 1). The recruitment of acetylated and unacetylated tropomyosin to distinct actin polymers permits the discrete regulation of specific myosins in fission yeast.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Banerjee S, et al. (2013 Aug). Splicing functions and global dependency on fission yeast slu7 reveal diversity in spliceosome assembly.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Hong H, et al. (2017 Apr 4). Molecular Basis of Substrate Specific Acetylation by N-Terminal Acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 7 genes with posterior transmembrane prediction > 50%