FOG13920
EOG8GTHWJ

sce:LSG1

Genes: 33

SGD Description
Putative GTPase involved in 60S ribosomal subunit biogenesis; required for the release of Nmd3p from 60S subunits in the cytoplasm


PomBase Description
GTP binding protein, HSR1-related (predicted)


AspGD Description
Ortholog(s) have mRNA binding activity and role in ascospore formation, conjugation with cellular fusion, ribosomal large subunit assembly, ribosomal subunit export from nucleus


References

Kallstrom G, et al. (2003 Jun). The putative GTPases Nog1p and Lsg1p are required for 60S ribosomal subunit biogenesis and are localized to the nucleus and cytoplasm, respectively.

Hedges J, et al. (2005 Feb 9). Release of the export adapter, Nmd3p, from the 60S ribosomal subunit requires Rpl10p and the cytoplasmic GTPase Lsg1p.

West M, et al. (2005 May). Defining the order in which Nmd3p and Rpl10p load onto nascent 60S ribosomal subunits.

Dong J, et al. (2005 Nov). The novel ATP-binding cassette protein ARB1 is a shuttling factor that stimulates 40S and 60S ribosome biogenesis.

Hedges J, et al. (2006 Dec 1). Mapping the functional domains of yeast NMD3, the nuclear export adapter for the 60 S ribosomal subunit.

Hofer A, et al. (2007 Nov 9). Mutational analysis of the ribosomal protein Rpl10 from yeast.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Liu NN, et al. (2010 Aug). A genome-wide screen for Schizosaccharomyces pombe deletion mutants that affect telomere length.

Ma Y, et al. (2011). Genome-wide screening for genes associated with FK506 sensitivity in fission yeast.

Nie M, et al. (2012 Aug 24). Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mojardín L, et al. (2015). Chromosome segregation and organization are targets of 5'-Fluorouracil in eukaryotic cells.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Hu L, et al. (2016 Aug). Genetic evidence for involvement of membrane trafficking in the action of 5-fluorouracil.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%