FOG13910
EOG8GTHZF
sce:SHR5
Genes: 23
SGD DescriptionPalmitoyltransferase subunit; this complex adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; palmitoylation is required for Ras2p membrane localization; Palmitoyltransferase is composed of Shr5p and Erf2
References
Jung V, et al. (1995 Mar). Mutations in the SHR5 gene of Saccharomyces cerevisiae suppress Ras function and block membrane attachment and palmitoylation of Ras proteins.
Zhao L, et al. (2002 Dec 20). Erf4p and Erf2p form an endoplasmic reticulum-associated complex involved in the plasma membrane localization of yeast Ras proteins.
Lobo S, et al. (2002 Oct 25). Identification of a Ras palmitoyltransferase in Saccharomyces cerevisiae.