FOG13764
EOG8H70Z6

sce:SDH7

Genes: 32

SGD Description
Mitochondrial protein involved in assembly of succinate dehydrogenase; has a role in maturation of the Sdh2p subunit; localized to the mitochondrial intermembrane space; required for acetate utilization and gluconeogenesis; mutation in Drosophila ortholog SDHAF3 causes reduced succinate dehydrogenase activity and neuronal and muscular dysfunction; member of the LYR protein family


PomBase Description
mitochondrial respiratory chain complex II assembly ACN9 family protein Sdh7 (predicted)


References

McCammon MT, et al. (1996 Sep). Mutants of Saccharomyces cerevisiae with defects in acetate metabolism: isolation and characterization of Acn- mutants.

Dennis RA, et al. (1999 Apr). Acn9 is a novel protein of gluconeogenesis that is located in the mitochondrial intermembrane space.

Dennis RA, et al. (1999 May 15). Yeast mutants of glucose metabolism with defects in the coordinate regulation of carbon assimilation.

Vögtle FN, et al. (2009 Oct 16). Global analysis of the mitochondrial N-proteome identifies a processing peptidase critical for protein stability.

Na U, et al. (2014 Aug 5). The LYR factors SDHAF1 and SDHAF3 mediate maturation of the iron-sulfur subunit of succinate dehydrogenase.

Chen JS, et al. (2016 Sep). Discovery of genes involved in mitosis, cell division, cell wall integrity and chromosome segregation through construction of Schizosaccharomyces pombe deletion strains.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%