FOG13709
EOG81C5B2
EOG8HDR88

sce:absent

Genes: 6

AspGD Description
Putative polyketide synthase (PKS), encoded in a predicted secondary metabolite gene cluster|Putative polyketide synthase (PKS), encoded in a predicted secondary metabolite gene cluster|Putative polyketide synthase (PKS) involved in both dihydroxynaphthalene (DHN) melanin and naphtho-gamma-pyrone production; required for wild-type black spore pigmentation; mutants have reduced ornamention on the conidial cell surface


References

PONTECORVO G, et al. (1953). The genetics of Aspergillus nidulans.

Clutterbuck AJ, et al. (1972 May). Absence of laccase from yellow-spored mutants of Aspergillus nidulans.

Clutterbuck AJ, et al. (1973 Jun). Gene symbols in Aspergillus nidulans.

Purnell DM, et al. (1978 Dec 18). Virulence genetics of Aspergillus nidulans Eidam: a review.

Kurtz MB, et al. (1982 Sep). Purification and characterization of the conidial laccase of Aspergillus nidulans.

Timberlake WE, et al. (1990). Molecular genetics of Aspergillus development.

Mayorga ME, et al. (1990 Sep). Isolation and molecular characterization of the Aspergillus nidulans wA gene.

Tilburn J, et al. (1990 Sep). Insertional inactivation and cloning of the wA gene of Aspergillus nidulans.

Marshall MA, et al. (1991 Jan). Aspergillus nidulans wetA activates spore-specific gene expression.

Mayorga ME, et al. (1992 Nov). The developmentally regulated Aspergillus nidulans wA gene encodes a polypeptide homologous to polyketide and fatty acid synthases.

Timberlake WE, et al. (1993 Oct). Translational Triggering and Feedback Fixation in the Control of Fungal Development.

Borgia PT, et al. (1994 Oct 1). Bidirectional gene transfer between Aspergillus fumigatus and Aspergillus nidulans.

Keller NP, et al. (1995). Analysis of a mycotoxin gene cluster in Aspergillus nidulans.

Chang PK, et al. (1995 Aug 21). The Aspergillus parasiticus polyketide synthase gene pksA, a homolog of Aspergillus nidulans wA, is required for aflatoxin B1 biosynthesis.

Albertini AM, et al. (1995 Feb). Sequence around the 159 degree region of the Bacillus subtilis genome: the pksX locus spans 33.6 kb.

Clutterbuck AJ, et al. (1997 Jun). The validity of the Aspergillus nidulans linkage map.

Guzmán-de-Peña D, et al. (1998 Feb). Correlation between the regulation of sterigmatocystin biosynthesis and asexual and sexual sporulation in Emericella nidulans.

Adams TH, et al. (1998 Mar). Asexual sporulation in Aspergillus nidulans.

Shuster JR, et al. (1999 Aug). Promoter-tagged restriction enzyme-mediated insertion (PT-REMI) mutagenesis in Aspergillus niger.

Dessen P, et al. (2000 Feb 22). The PAUSE software for analysis of translational control over protein targeting: application to E. nidulans membrane proteins.

Jahn B, et al. (2000 Jun). Interaction of human phagocytes with pigmentless Aspergillus conidia.

Fujii I, et al. (2001 Feb). Identification of Claisen cyclase domain in fungal polyketide synthase WA, a naphthopyrone synthase of Aspergillus nidulans.

Varga J, et al. (2003 Oct). Diversity of polyketide synthase gene sequences in Aspergillus species.

Graziani S, et al. (2004 May). Novel polyketide synthase from Nectria haematococca.

Souza-Júnior SA, et al. (2005 May). Chlorhexidine digluconate induces mitotic recombination in diploid cells of Aspergillus nidulans.

Forment JV, et al. (2006 Sep). Consecutive gene deletions in Aspergillus nidulans: application of the Cre/loxP system.

Harris SD, et al. (2009 Mar). Morphology and development in Aspergillus nidulans: a complex puzzle.

von Döhren H, et al. (2009 Mar). A survey of nonribosomal peptide synthetase (NRPS) genes in Aspergillus nidulans.

Schoustra S, et al. (2010 Aug 10). Fitness-associated sexual reproduction in a filamentous fungus.

Nielsen ML, et al. (2011 Aug). A genome-wide polyketide synthase deletion library uncovers novel genetic links to polyketides and meroterpenoids in Aspergillus nidulans.

Volling K, et al. (2011 Aug). Phagocytosis of melanized Aspergillus conidia by macrophages exerts cytoprotective effects by sustained PI3K/Akt signalling.

Matsuhira K, et al. (2012). Improvement of gene targeting in Aspergillus nidulans with excess non-homologous fragments.

Slesiona S, et al. (2012). Persistence versus escape: Aspergillus terreus and Aspergillus fumigatus employ different strategies during interactions with macrophages.

Sanchez JF, et al. (2012 Mar). Advances in Aspergillus secondary metabolite research in the post-genomic era.

Liu T, et al. (2014 Mar 21). Rational domain swaps reveal insights about chain length control by ketosynthase domains in fungal nonreducing polyketide synthases.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%

FOG13710
EOG8HDR88

sce:absent

Genes: 1

Parent
paralog:FOG13709


AspGD Description
Putative polyketide synthase (PKS), encoded in a predicted secondary metabolite gene cluster


References

Szewczyk E, et al. (2008 Dec). Identification and characterization of the asperthecin gene cluster of Aspergillus nidulans.

Bok JW, et al. (2009 Jul). Chromatin-level regulation of biosynthetic gene clusters.

von Döhren H, et al. (2009 Mar). A survey of nonribosomal peptide synthetase (NRPS) genes in Aspergillus nidulans.

Chiang YM, et al. (2010 Apr). Characterization of the Aspergillus nidulans monodictyphenone gene cluster.

Nielsen ML, et al. (2011 Aug). A genome-wide polyketide synthase deletion library uncovers novel genetic links to polyketides and meroterpenoids in Aspergillus nidulans.

Sanchez JF, et al. (2011 Mar 23). Genome-based deletion analysis reveals the prenyl xanthone biosynthesis pathway in Aspergillus nidulans.

Sarkar A, et al. (2012 Jul 31). Differential expression of silent polyketide biosynthesis gene clusters in chemostat cultures of Aspergillus nidulans.

Sanchez JF, et al. (2012 Mar). Advances in Aspergillus secondary metabolite research in the post-genomic era.

Ahuja M, et al. (2012 May 16). Illuminating the diversity of aromatic polyketide synthases in Aspergillus nidulans.

Liu T, et al. (2014 Mar 21). Rational domain swaps reveal insights about chain length control by ketosynthase domains in fungal nonreducing polyketide synthases.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%