FOG13616
EOG8HMGV9

sce:CAP2

Genes: 32

SGD Description
Beta subunit of the capping protein heterodimer (Cap1p and Cap2p); capping protein (CP) binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches; protein increases in abundance and relocalizes from bud neck to plasma membrane upon DNA replication stress


PomBase Description
F-actin capping protein beta subunit Acp2


AspGD Description
Ortholog(s) have actin filament binding activity and role in barbed-end actin filament capping, filamentous growth, mitotic actomyosin contractile ring contraction


References

Cannon JF, et al. (1987 Aug). Characterization of Saccharomyces cerevisiae genes encoding subunits of cyclic AMP-dependent protein kinase.

Amatruda JF, et al. (1990 Mar 22). Disruption of the actin cytoskeleton in yeast capping protein mutants.

Amatruda JF, et al. (1992 Jun). Purification, characterization, and immunofluorescence localization of Saccharomyces cerevisiae capping protein.

Wu JQ, et al. (2003 Nov). Spatial and temporal pathway for assembly and constriction of the contractile ring in fission yeast cytokinesis.

Kovar DR, et al. (2005 May). Profilin-mediated competition between capping protein and formin Cdc12p during cytokinesis in fission yeast.

Nakano K, et al. (2005 Nov 21). Stg 1 is a novel SM22/transgelin-like actin-modulating protein in fission yeast.

Wu JQ, et al. (2005 Oct 14). Counting cytokinesis proteins globally and locally in fission yeast.

Nakano K, et al. (2006 Apr). Actin-depolymerizing protein Adf1 is required for formation and maintenance of the contractile ring during cytokinesis in fission yeast.

Nakano K, et al. (2006 Aug). Actin-capping protein is involved in controlling organization of actin cytoskeleton together with ADF/cofilin, profilin and F-actin crosslinking proteins in fission yeast.

Dixon SJ, et al. (2008 Oct 28). Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Liu NN, et al. (2010 Aug). A genome-wide screen for Schizosaccharomyces pombe deletion mutants that affect telomere length.

Sirotkin V, et al. (2010 Aug 15). Quantitative analysis of the mechanism of endocytic actin patch assembly and disassembly in fission yeast.

Skau CT, et al. (2011 Jul 29). Actin filament bundling by fimbrin is important for endocytosis, cytokinesis, and polarization in fission yeast.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Berro J, et al. (2014 Nov 5). Synergies between Aip1p and capping protein subunits (Acp1p and Acp2p) in clathrin-mediated endocytosis and cell polarization in fission yeast.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Laporte D, et al. (2015 Jul 6). A stable microtubule array drives fission yeast polarity reestablishment upon quiescence exit.

Baker K, et al. (2016 Jul 1). TOR complex 2 localises to the cytokinetic actomyosin ring and controls the fidelity of cytokinesis.

Guo L, et al. (2016 Oct 13). Global Fitness Profiling Identifies Arsenic and Cadmium Tolerance Mechanisms in Fission Yeast.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%