FOG13599
EOG8HQC04

sce:CWH43

Genes: 33

SGD Description
Putative sensor/transporter protein involved in cell wall biogenesis; contains 14-16 transmembrane segments and several putative glycosylation and phosphorylation sites; null mutation is synthetically lethal with pkc1 deletion


PomBase Description
glycosylceramide biosynthesis protein Cwh43 (predicted)


AspGD Description
Similar to protein involved in of cell wall biogenesis; expression repressed by tunicamycin and DTT


References

Martin-Yken H, et al. (2001 Jun 30). Saccharomyces cerevisiae YCRO17c/CWH43 encodes a putative sensor/transporter protein upstream of the BCK2 branch of the PKC1-dependent cell wall integrity pathway.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Fujioka T, et al. (2007 Aug). MpkA-Dependent and -independent cell wall integrity signaling in Aspergillus nidulans.

Umemura M, et al. (2007 Nov). Saccharomyces cerevisiae CWH43 is involved in the remodeling of the lipid moiety of GPI anchors to ceramides.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Ghugtyal V, et al. (2007 Sep). CWH43 is required for the introduction of ceramides into GPI anchors in Saccharomyces cerevisiae.

Futagami T, et al. (2012 Mar 1). Putative cell wall integrity sensor proteins in Aspergillus nidulans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 33 genes with posterior transmembrane prediction > 50%