FOG13476
EOG8HX3N0

sce:GAR1

Genes: 33

SGD Description
Protein component of the H/ACA snoRNP pseudouridylase complex; involved in the modification and cleavage of the 18S pre-rRNA


PomBase Description
snoRNP pseudouridylase box H/ACA snoRNP complex protein Gar1


AspGD Description
Ortholog(s) have nucleolus localization


References

Girard JP, et al. (1992 Feb). GAR1 is an essential small nucleolar RNP protein required for pre-rRNA processing in yeast.

Girard JP, et al. (1993 May 11). The SpGAR1 gene of Schizosaccharomyces pombe encodes the functional homologue of the snoRNP protein GAR1 of Saccharomyces cerevisiae.

Gulli MP, et al. (1995 Jun 11). gar2 is a nucleolar protein from Schizosaccharomyces pombe required for 18S rRNA and 40S ribosomal subunit accumulation.

Bousquet-Antonelli C, et al. (1997 Aug 1). A small nucleolar RNP protein is required for pseudouridylation of eukaryotic ribosomal RNAs.

Gulli MP, et al. (1997 Jun). Mitosis-specific phosphorylation of gar2, a fission yeast nucleolar protein structurally related to nucleolin.

Henras A, et al. (1998 Dec 1). Nhp2p and Nop10p are essential for the function of H/ACA snoRNPs.

Bagni C, et al. (1998 May 1). Gar1p binds to the small nucleolar RNAs snR10 and snR30 in vitro through a nontypical RNA binding element.

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Xu C, et al. (2003 Jun). In vivo analysis of nucleolar proteins modified by the yeast arginine methyltransferase Hmt1/Rmt1p.

Henras AK, et al. (2004 Nov). Cbf5p, the putative pseudouridine synthase of H/ACA-type snoRNPs, can form a complex with Gar1p and Nop10p in absence of Nhp2p and box H/ACA snoRNAs.

Perreault A, et al. (2007 Mar 9). Regulation of the nuclear poly(A)-binding protein by arginine methylation in fission yeast.

Singh NS, et al. (2011 Dec 6). SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast.

Ren L, et al. (2011 Feb 28). Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19.

Zhang K, et al. (2011 Mar 25). Clr4/Suv39 and RNA quality control factors cooperate to trigger RNAi and suppress antisense RNA.

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

Li S, et al. (2011 Nov 15). Reconstitution and structural analysis of the yeast box H/ACA RNA-guided pseudouridine synthase.

Li S, et al. (2011 Nov 25). Structure of the Shq1-Cbf5-Nop10-Gar1 complex and implications for H/ACA RNP biogenesis and dyskeratosis congenita.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Grenier St-Sauveur V, et al. (2013 Dec). Poly(A) tail-mediated gene regulation by opposing roles of Nab2 and Pab2 nuclear poly(A)-binding proteins in pre-mRNA decay.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mathiassen SG, et al. (2015 Aug 21). A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%