FOG13433
EOG8J0ZWW

sce:TPA1

Genes: 33

SGD Description
Fe(II)/2-oxoglutarate-dependent dioxygenase family member; catalyzes the repair of methyl-base lesions in both ss and dsDNA by oxidative demethylation; Poly(rA)-binding protein involved in mRNA poly(A) tail length and mRNA stability; role in translation termination efficiency; interacts with Sup45p (eRF1), Sup35p (eRF3) and Pab1p; similar to human prolyl 4-hydroxylase OGFOD1; binds Fe(II) and 2-oxoglutarate


PomBase Description
2-oxoglutarate and Fe(II) dioxygenase domain containing protein 1


AspGD Description
Ortholog(s) have peptidyl-proline dioxygenase activity


References

Hughes BT, et al. (2008 May 21). Oxygen-regulated degradation of fission yeast SREBP by Ofd1, a prolyl hydroxylase family member.

Roberts-Galbraith RH, et al. (2009 Jan 12). The SH3 domains of two PCH family members cooperate in assembly of the Schizosaccharomyces pombe contractile ring.

Hagiwara D, et al. (2009 Nov). Transcriptional profiling for Aspergillusnidulans HogA MAPK signaling pathway in response to fludioxonil and osmotic stress.

Takeda K, et al. (2011). Identification of genes affecting the toxicity of anti-cancer drug bortezomib by genome-wide screening in S. pombe.

Yeh TL, et al. (2011 Apr 13). The hypoxic regulator of sterol synthesis nro1 is a nuclear import adaptor.

Lee CY, et al. (2011 Oct 21). Regulation of the Sre1 hypoxic transcription factor by oxygen-dependent control of DNA binding.

Chen Z, et al. (2012 Oct). A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Brookheart RT, et al. (2014 Jan 31). Casein kinase 1 regulates sterol regulatory element-binding protein (SREBP) to control sterol homeostasis.

Loenarz C, et al. (2014 Mar 18). Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%