FOG13386
EOG8J3V39

sce:DUO1

Genes: 5

SGD Description
Essential subunit of the Dam1 complex (aka DASH complex); cooperates with Dam1p to connect the DASH complex with microtubules (MT); couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis


References

Feuermann M, et al. (1997 Jul). The characterization of two new clusters of duplicated genes suggests a 'Lego' organization of the yeast Saccharomyces cerevisiae chromosomes.

Hofmann C, et al. (1998 Nov 16). Saccharomyces cerevisiae Duo1p and Dam1p, novel proteins involved in mitotic spindle function.

Miranda JJ, et al. (2005 Feb). The yeast DASH complex forms closed rings on microtubules.

Westermann S, et al. (2005 Jan 21). Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex.

Joglekar AP, et al. (2006 Jun). Molecular architecture of a kinetochore-microtubule attachment site.

Asbury CL, et al. (2006 Jun 27). The Dam1 kinetochore complex harnesses microtubule dynamics to produce force and movement.

Westermann S, et al. (2006 Mar 23). The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%