FOG13238
EOG8JM64R

sce:APP1

Genes: 32

SGD Description
Phosphatidate phosphatase, converts phosphatidate to diacylglycerol; App1p, Pah1p, Dpp1p, and Lpp1p are responsible for all the phosphatidate phosphatase activity; component of cortical actin patches; interacts with components of endocytic pathway


PomBase Description
actin cortical patch protein (predicted)


AspGD Description
Ortholog(s) have role in receptor-mediated endocytosis and actin cortical patch localization


References

Drees BL, et al. (2001 Aug 6). A protein interaction map for cell polarity development.

Landgraf C, et al. (2004 Jan). Protein interaction networks by proteome peptide scanning.

Kung LA, et al. (2009). Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals new roles for protein glycosylation in eukaryotes.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Chae M, et al. (2012 Nov 23). The Saccharomyces cerevisiae actin patch protein App1p is a phosphatidate phosphatase enzyme.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30<sup>Fft3</sup> induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50%