FOG13219
EOG8JM69F

sce:TRS20

Genes: 31

SGD Description
Core component of transport protein particle (TRAPP) complexes I-III; TRAPP complexes are related multimeric guanine nucleotide-exchange factors for the GTPase Ypt1p, regulating ER-Golgi traffic (TRAPPI), intra-Golgi traffic (TRAPPII), endosome-Golgi traffic (TRAPPII and III) and autophagy (TRAPPIII); mutation of conserved residues leads to defects in endocytic recycling and a block in sporulation/meiosis; mutations in the human homolog cause the spondyloepiphyseal dysplasia


PomBase Description
TRAPP complex subunit Trs20 (predicted)


References

Sacher M, et al. (1998 May 1). TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion.

Sacher M, et al. (2001 Feb). TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport.

Lynch-Day MA, et al. (2010 Apr 27). Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy.

Yip CK, et al. (2010 Nov). Molecular architecture of the TRAPPII complex and implications for vesicle tethering.

Pinar M, et al. (2015 Apr 7). TRAPPII regulates exocytic Golgi exit by mediating nucleotide exchange on the Ypt31 ortholog RabERAB11.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%