FOG13182
EOG8JQ2GP

sce:SMP3

Genes: 31

SGD Description
Alpha 1,2-mannosyltransferase; involved in glycosyl phosphatidyl inositol (GPI) biosynthesis; required for addition of the fourth, side branching mannose to the GPI core structure


PomBase Description
alpha-1,2-mannosyltransferase (predicted)


References

Irie K, et al. (1991 Feb). Mutations in a Saccharomyces cerevisiae host showing increased holding stability of the heterologous plasmid pSR1.

Grimme SJ, et al. (2001 Jul 20). The essential Smp3 protein is required for addition of the side-branching fourth mannose during assembly of yeast glycosylphosphatidylinositols.

Grimme SJ, et al. (2004 Oct). Deficiencies in the essential Smp3 mannosyltransferase block glycosylphosphatidylinositol assembly and lead to defects in growth and cell wall biogenesis in Candida albicans.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 31 genes with posterior transmembrane prediction > 50%