FOG12998
EOG8K6DKT

sce:RFC1

Genes: 33

SGD Description
Subunit of heteropentameric Replication factor C (RF-C); RF-C is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon


PomBase Description
DNA replication factor C complex subunit Rfc1


AspGD Description
Ortholog(s) have role in DNA strand elongation involved in DNA replication, UV-damage excision repair, mitotic DNA replication and Elg1 RFC-like complex, nucleus localization


References

Howell EA, et al. (1994 Jan). CDC44: a putative nucleotide-binding protein required for cell cycle progression that has homology to subunits of replication factor C.

Cullmann G, et al. (1995 Sep). Characterization of the five replication factor C genes of Saccharomyces cerevisiae.

Kenna MA, et al. (2003 Apr). Mechanical link between cohesion establishment and DNA replication: Ctf7p/Eco1p, a cohesion establishment factor, associates with three different replication factor C complexes.

Yao N, et al. (2003 Dec 12). Replication factor C clamp loader subunit arrangement within the circular pentamer and its attachment points to proliferating cell nuclear antigen.

Bowman GD, et al. (2004 Jun 17). Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex.

Bylund GO, et al. (2005 Jul). Replication protein A-directed unloading of PCNA by the Ctf18 cohesion establishment complex.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50%