FOG12987
EOG8K6DNC

sce:SSF1;SSF2

Genes: 35

SGD Description
Constituent of 66S pre-ribosomal particles; required for ribosomal large subunit maturation; functionally redundant with Ssf2p; member of the Brix family; SSF1 has a paralog, SSF2, that arose from the whole genome duplication|Protein required for ribosomal large subunit maturation; functionally redundant with Ssf1p; member of the Brix family; SSF2 has a paralog, SSF1, that arose from the whole genome duplication


PomBase Description
RNA-binding protein involved in ribosomal large subunit assembly and maintenance (predicted)


AspGD Description
Ortholog(s) have rRNA binding activity and role in conjugation with cellular fusion, maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), regulation of cell size, ribosomal large subunit assembly


References

Yu Y, et al. (1995 May). An essential gene pair in Saccharomyces cerevisiae with a potential role in mating.

Kim J, et al. (1998 Jun). A nucleolar protein that affects mating efficiency in Saccharomyces cerevisiae by altering the morphological response to pheromone.

Fatica A, et al. (2002 Feb). Ssf1p prevents premature processing of an early pre-60S ribosomal particle.

Bogengruber E, et al. (2003 Mar). Functional analysis in yeast of the Brix protein superfamily involved in the biogenesis of ribosomes.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 30 genes with posterior transmembrane prediction > 50%