FOG12946
EOG8K98VM

sce:IPI1

Genes: 31

SGD Description
Component of the Rix1 complex and possibly pre-replicative complexes; required for processing of ITS2 sequences from 35S pre-rRNA; component of the pre-60S ribosomal particle with the dynein-related AAA-type ATPase Mdn1p; required for pre-replicative complex (pre-RC) formation and maintenance during DNA replication licensing; relocalizes to the cytosol in response to hypoxia; essential gene


PomBase Description
rRNA processing protein Ipi1 (predicted)


References

Hazbun TR, et al. (2003 Dec). Assigning function to yeast proteins by integration of technologies.

Galani K, et al. (2004 Dec 31). Rea1, a dynein-related nuclear AAA-ATPase, is involved in late rRNA processing and nuclear export of 60 S subunits.

Krogan NJ, et al. (2004 Jan 30). High-definition macromolecular composition of yeast RNA-processing complexes.

Nissan TA, et al. (2004 Jul 23). A pre-ribosome with a tadpole-like structure functions in ATP-dependent maturation of 60S subunits.

Barrio-Garcia C, et al. (2016 Jan). Architecture of the Rix1-Rea1 checkpoint machinery during pre-60S-ribosome remodeling.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 6 genes with posterior transmembrane prediction > 50%