FOG12838
EOG8KH1FQ

sce:UBC12

Genes: 31

SGD Description
Enzyme that mediates the conjugation of Rub1p; a ubiquitin-like protein, to other proteins; related to E2 ubiquitin-conjugating enzymes


PomBase Description
NEDD8-conjugating enzyme Ubc12


AspGD Description
Ortholog(s) have role in regulation of mitotic cell cycle and cytosol, nucleus localization


References

Liakopoulos D, et al. (1998 Apr 15). A novel protein modification pathway related to the ubiquitin system.

Osaka F, et al. (2000 Jul 3). Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast.

Scott DC, et al. (2011 Nov 4). N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex.

von Zeska Kress MR, et al. (2012 Mar). The COP9 signalosome counteracts the accumulation of cullin SCF ubiquitin E3 RING ligases during fungal development.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 6 genes with posterior transmembrane prediction > 50%