FOG12786
EOG8KPRRS

sce:CRM1

Genes: 34

SGD Description
Major karyopherin; involved in export of proteins, RNAs, and ribosomal subunits from the nucleus; exportin


PomBase Description
importin family nuclear export receptor Crm1


AspGD Description
Ortholog(s) have nuclear export signal receptor activity, role in cellular response to oxidative stress, protein export from nucleus and cytosol, nuclear envelope, nuclear periphery localization


References

Toda T, et al. (1992 Dec). Fission yeast pap1-dependent transcription is negatively regulated by an essential nuclear protein, crm1.

Stade K, et al. (1997 Sep 19). Exportin 1 (Crm1p) is an essential nuclear export factor.

Murphy MW, et al. (2004 Jan). The yeast splicing factor Prp40p contains functional leucine-rich nuclear export signals that are essential for splicing.

Brune C, et al. (2005 Apr). Yeast poly(A)-binding protein Pab1 shuttles between the nucleus and the cytoplasm and functions in mRNA export.

Todd RB, et al. (2005 Oct). Nuclear accumulation of the GATA factor AreA in response to complete nitrogen starvation by regulation of nuclear export.

Bernreiter A, et al. (2007 Feb). Nuclear export of the transcription factor NirA is a regulatory checkpoint for nitrate induction in Aspergillus nidulans.

Miskei M, et al. (2009 Mar). Annotation of stress-response proteins in the aspergilli.

Markina-Iñarrairaegui A, et al. (2011 Oct). Nuclear transporters in a multinucleated organism: functional and localization analyses in Aspergillus nidulans.

Gallmetzer A, et al. (2015 Jul). Reversible Oxidation of a Conserved Methionine in the Nuclear Export Sequence Determines Subcellular Distribution and Activity of the Fungal Nitrate Regulator NirA.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%