FOG12777
EOG8KPRT4

sce:RPN9

Genes: 32

SGD Description
Non-ATPase regulatory subunit of the 26S proteasome; similar to putative proteasomal subunits in other species; null mutant is temperature sensitive and exhibits cell cycle and proteasome assembly defects; protein abundance increases in response to DNA replication stress; relocalizes to the cytosol in response to hypoxia


PomBase Description
19S proteasome regulatory subunit Rpn9


AspGD Description
Ortholog of A. nidulans FGSC A4 : AN3716, A. fumigatus Af293 : Afu6g12770, A. oryzae RIB40 : AO090003000397, Aspergillus wentii : Aspwe1_0102826 and Aspergillus sydowii : Aspsy1_0032599


References

Hori T, et al. (1998 Aug 17). cDNA cloning and functional analysis of p28 (Nas6p) and p40.5 (Nas7p), two novel regulatory subunits of the 26S proteasome.

Wilkinson CR, et al. (1998 Nov 16). Localization of the 26S proteasome during mitosis and meiosis in fission yeast.

Yen HC, et al. (2003 Aug 15). Rpn5 is a conserved proteasome subunit and required for proper proteasome localization and assembly.

Kimura Y, et al. (2003 Jan 15). N-Terminal modifications of the 19S regulatory particle subunits of the yeast proteasome.

MacKenzie DA, et al. (2005 Nov). UPR-independent dithiothreitol stress-induced genes in Aspergillus niger.

Sha Z, et al. (2007 Nov 2). Isolation of the Schizosaccharomyces pombe proteasome subunit Rpn7 and a structure-function study of the proteasome-COP9-initiation factor domain.

Bohn S, et al. (2010 Dec 7). Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution.

Takeda K, et al. (2010 Feb 23). Synergistic roles of the proteasome and autophagy for mitochondrial maintenance and chronological lifespan in fission yeast.

Kouranti I, et al. (2010 Sep 7). A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarity.

Singh NS, et al. (2011 Dec 6). SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast.

Penney M, et al. (2012). Fission yeast 26S proteasome mutants are multi-drug resistant due to stabilization of the Pap1 transcription factor.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Beck F, et al. (2012 Sep 11). Near-atomic resolution structural model of the yeast 26S proteasome.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%