FOG12731
EOG8KSN30

sce:JHD1

Genes: 30

SGD Description
JmjC domain family histone demethylase specific for H3-K36; similar to proteins found in human, mouse, drosophila, X. laevis, C. elegans, and S. pombe


PomBase Description
Jmjc domain chromatin associated protein Epe1


AspGD Description
Has domain(s) with predicted zinc ion binding activity


References

Ayoub N, et al. (2003 Jun). A novel jmjC domain protein modulates heterochromatization in fission yeast.

Tsukada Y, et al. (2006 Feb 16). Histone demethylation by a family of JmjC domain-containing proteins.

Zofall M, et al. (2006 Jun 9). Swi6/HP1 recruits a JmjC domain protein to facilitate transcription of heterochromatic repeats.

Isaac S, et al. (2007 Apr). Interaction of Epe1 with the heterochromatin assembly pathway in Schizosaccharomyces pombe.

Trewick SC, et al. (2007 Nov 14). The JmjC domain protein Epe1 prevents unregulated assembly and disassembly of heterochromatin.

Sadaie M, et al. (2008 Dec). Balance between distinct HP1 family proteins controls heterochromatin assembly in fission yeast.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Braun S, et al. (2011 Jan 7). The Cul4-Ddb1(Cdt)² ubiquitin ligase inhibits invasion of a boundary-associated antisilencing factor into heterochromatin.

Chen Z, et al. (2012 Oct). A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.

Sun LL, et al. (2013). Global analysis of fission yeast mating genes reveals new autophagy factors.

Tashiro S, et al. (2013 Apr). Transcription-induced chromatin association of RNA surveillance factors mediates facultative heterochromatin formation in fission yeast.

Aygün O, et al. (2013 May). HDAC-mediated suppression of histone turnover promotes epigenetic stability of heterochromatin.

Wang J, et al. (2013 Sep 1). Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries.

Bayne EH, et al. (2014). A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast.

Sideri T, et al. (2014 Dec 1). Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.

Rallis C, et al. (2014 Feb 15). Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth.

Sadeghi L, et al. (2015 Dec). The Paf1 complex factors Leo1 and Paf1 promote local histone turnover to modulate chromatin states in fission yeast.

Wang J, et al. (2015 Mar 16). Rapid epigenetic adaptation to uncontrolled heterochromatin spreading.

Verrier L, et al. (2015 May). Global regulation of heterochromatin spreading by Leo1.

Garcia JF, et al. (2015 May 8). Intrinsic Toxicity of Unchecked Heterochromatin Spread Is Suppressed by Redundant Chromatin Boundary Functions in Schizosacchromyces pombe.

Wang J, et al. (2016 Apr 1). The proper connection between shelterin components is required for telomeric heterochromatin assembly.

Swaffer MP, et al. (2016 Dec 15). CDK Substrate Phosphorylation and Ordering the Cell Cycle.

Barrales RR, et al. (2016 Jan 15). Control of heterochromatin localization and silencing by the nuclear membrane protein Lem2.

Shan CM, et al. (2016 Sep 20). A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Chen Y, et al. (2017 Jun 9). Epe1 contributes to activation of AMPK by promoting phosphorylation of AMPK alpha subunit, Ssp2.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%