FOG12494
EOG86M918
EOG8MCVGW

sce:RSC3

Genes: 4

SGD Description
Component of the RSC chromatin remodeling complex; essential gene required for maintenance of proper ploidy and regulation of ribosomal protein genes and the cell wall/stress response; RSC3 has a paralog, RSC30, that arose from the whole genome duplication


References

Cairns BR, et al. (1996 Dec 27). RSC, an essential, abundant chromatin-remodeling complex.

Lorch Y, et al. (1999 Feb 5). Histone octamer transfer by a chromatin-remodeling complex.

Moreira JM, et al. (1999 May 17). Transcriptional repression of the yeast CHA1 gene requires the chromatin-remodeling complex RSC.

Cairns BR, et al. (1999 Nov). Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains.

Angus-Hill ML, et al. (2001 Apr). A Rsc3/Rsc30 zinc cluster dimer reveals novel roles for the chromatin remodeler RSC in gene expression and cell cycle control.

Saha A, et al. (2002 Aug 15). Chromatin remodeling by RSC involves ATP-dependent DNA translocation.

Chai B, et al. (2002 Jun). Yeast RSC function is required for organization of the cellular cytoskeleton via an alternative PKC1 pathway.

Hsu JM, et al. (2003 May). The yeast RSC chromatin-remodeling complex is required for kinetochore function in chromosome segregation.

Wilson B, et al. (2006 Feb). The RSC chromatin remodeling complex bears an essential fungal-specific protein module with broad functional roles.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%