FOG12487
EOG889351
EOG8MCVHM

sce:MAK11

Genes: 34

SGD Description
Protein involved in an early step of 60S ribosomal subunit biogenesis; essential for cell growth and replication of killer M1 dsRNA virus; contains four beta-transducin repeats


PomBase Description
p21 activated protein kinase inhibitor Skb15


AspGD Description
Ortholog(s) have protein kinase inhibitor activity


References

Icho T, et al. (1988 Jan 25). The MAK11 protein is essential for cell growth and replication of M double-stranded RNA and is apparently a membrane-associated protein.

Ohtake Y, et al. (1995 May). Yeast virus propagation depends critically on free 60S ribosomal subunit concentration.

Kim HW, et al. (2001 May). Genetic and molecular characterization of Skb15, a highly conserved inhibitor of the fission yeast PAK, Shk1.

Qyang Y, et al. (2002 Apr). The p21-activated kinase, Shk1, is required for proper regulation of microtubule dynamics in the fission yeast, Schizosaccharomyces pombe.

Nissan TA, et al. (2002 Oct 15). 60S pre-ribosome formation viewed from assembly in the nucleolus until export to the cytoplasm.

Kim H, et al. (2003 Aug 8). The kelch repeat protein, Tea1, is a potential substrate target of the p21-activated kinase, Shk1, in the fission yeast, Schizosaccharomyces pombe.

Saveanu C, et al. (2003 Jul). Sequential protein association with nascent 60S ribosomal particles.

Saveanu C, et al. (2007 Apr). The p21-activated protein kinase inhibitor Skb15 and its budding yeast homologue are 60S ribosome assembly factors.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%