FOG12290
EOG8MW6Q5

sce:RRP42

Genes: 32

SGD Description
Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp42p (EXOSC7)


PomBase Description
exosome subunit Rrp42


AspGD Description
Ortholog(s) have role in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), nuclear polyadenylation-dependent tRNA catabolic process, rRNA catabolic process


References

Mitchell P, et al. (1997 Nov 14). The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases.

Allmang C, et al. (1999 Aug 15). The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases.

Liu Q, et al. (2006 Dec 15). Reconstitution, activities, and structure of the eukaryotic RNA exosome.

Dziembowski A, et al. (2007 Jan). A single subunit, Dis3, is essentially responsible for yeast exosome core activity.

Hagiwara D, et al. (2009 Nov). Transcriptional profiling for Aspergillusnidulans HogA MAPK signaling pathway in response to fludioxonil and osmotic stress.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 21 genes with posterior transmembrane prediction > 50%