FOG12168
EOG8N5TGJ

sce:SNF7

Genes: 32

SGD Description
One of four subunits of the ESCRT-III complex; involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway; recruited from the cytoplasm to endosomal membranes; ESCRT-III stands for endosomal sorting complex required for transport III


PomBase Description
ESCRT III complex subunit Vps32


AspGD Description
Ortholog(s) have role in cellular response to anoxia, cellular response to drug, cellular response to lithium ion and cellular response to pH, more


References

Robinson JS, et al. (1988 Nov). Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases.

Vallier LG, et al. (1991 Nov). New SNF genes, GAL11 and GRR1 affect SUC2 expression in Saccharomyces cerevisiae.

Tu J, et al. (1993 Sep). Molecular and genetic analysis of the SNF7 gene in Saccharomyces cerevisiae.

Amerik AY, et al. (2000 Oct). The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways.

Howard TL, et al. (2001 Jul). CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins.

Babst M, et al. (2002 Aug). Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting.

Kullas AL, et al. (2004 Dec). Snf7p, a component of the ESCRT-III protein complex, is an upstream member of the RIM101 pathway in Candida albicans.

Bowers K, et al. (2004 Mar). Protein-protein interactions of ESCRT complexes in the yeast Saccharomyces cerevisiae.

Kim J, et al. (2005 Jun). Structural basis for endosomal targeting by the Bro1 domain.

Lottridge JM, et al. (2006 Apr 18). Vta1p and Vps46p regulate the membrane association and ATPase activity of Vps4p at the yeast multivesicular body.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Teis D, et al. (2008 Oct). Ordered assembly of the ESCRT-III complex on endosomes is required to sequester cargo during MVB formation.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Sciskala B, et al. (2013 Nov). Interaction maps of the Saccharomyces cerevisiae ESCRT-III protein Snf7.

Buchkovich NJ, et al. (2013 Oct 28). Essential N-terminal insertion motif anchors the ESCRT-III filament during MVB vesicle formation.

Adell MA, et al. (2014 Apr 14). Coordinated binding of Vps4 to ESCRT-III drives membrane neck constriction during MVB vesicle formation.

Webster BM, et al. (2014 Oct 9). Surveillance of nuclear pore complex assembly by ESCRT-III/Vps4.

Tang S, et al. (2015 Dec 15). Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments.

Wolters N, et al. (2015 Nov 20). The N-terminal domains determine cellular localization and functions of the Doa4 and Ubp5 deubiquitinating enzymes.

Chiaruttini N, et al. (2015 Nov 5). Relaxation of Loaded ESCRT-III Spiral Springs Drives Membrane Deformation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%