FOG12058
EOG8NGF4W

sce:SCC4

Genes: 5

SGD Description
Subunit of cohesin loading factor (Scc2p-Scc4p); complex is required for the loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during double-strand break repair via phosphorylated histone H2AX


References

Ciosk R, et al. (2000 Feb). Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Lopez-Serra L, et al. (2014 Oct). The Scc2-Scc4 complex acts in sister chromatid cohesion and transcriptional regulation by maintaining nucleosome-free regions.

Hinshaw SM, et al. (2015 Jun 3). Structural evidence for Scc4-dependent localization of cohesin loading.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%