FOG12021
EOG8NK9BS

sce:CSG2

Genes: 4

SGD Description
Endoplasmic reticulum membrane protein; required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations; protein abundance increases in response to DNA replication stress


References

Schulze M, et al. (1989 Mar). Accumulation of the cytochrome c oxidase subunits I and II in yeast requires a mitochondrial membrane-associated protein, encoded by the nuclear SCO1 gene.

Beeler T, et al. (1994 Mar 11). A novel protein, CSG2p, is required for Ca2+ regulation in Saccharomyces cerevisiae.

Takita Y, et al. (1995 Feb 6). The CLS2 gene encodes a protein with multiple membrane-spanning domains that is important Ca2+ tolerance in yeast.

Uemura S, et al. (2003 Nov 14). Csg1p and newly identified Csh1p function in mannosylinositol phosphorylceramide synthesis by interacting with Csg2p.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%