FOG11818
EOG8P2NN8

sce:YIP1

Genes: 33

SGD Description
Integral membrane protein; required for the biogenesis of ER-derived COPII transport vesicles; interacts with Yif1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles; homolog of human YIPF4


PomBase Description
Rab GTPase binding (predicted)


AspGD Description
Ortholog(s) have role in ER to Golgi vesicle-mediated transport, cellular response to drug, vesicle fusion with Golgi apparatus


References

Yang X, et al. (1998 Sep 1). Specific binding to a novel and essential Golgi membrane protein (Yip1p) functionally links the transport GTPases Ypt1p and Ypt31p.

Matern H, et al. (2000 Sep 1). A novel Golgi membrane protein is part of a GTPase-binding protein complex involved in vesicle targeting.

Calero M, et al. (2001 Apr 13). Yop1p, the yeast homolog of the polyposis locus protein 1, interacts with Yip1p and negatively regulates cell growth.

Calero M, et al. (2002 Jan 18). Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins.

Calero M, et al. (2003 May). Dual prenylation is required for Rab protein localization and function.

Barrowman J, et al. (2003 May 30). The Yip1p.Yif1p complex is required for the fusion competence of endoplasmic reticulum-derived vesicles.

Chen CZ, et al. (2004 Dec). Genetic analysis of yeast Yip1p function reveals a requirement for Golgi-localized rab proteins and rab-Guanine nucleotide dissociation inhibitor.

Vollert CS, et al. (2004 Nov). The phox homology (PX) domain protein interaction network in yeast.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 33 genes with posterior transmembrane prediction > 50%