FOG11635
EOG8PK0TC

sce:BUD23

Genes: 34

SGD Description
Methyltransferase; methylates residue G1575 of 18S rRNA; required for rRNA processing and nuclear export of 40S ribosomal subunits independently of methylation activity; diploid mutant displays random budding pattern


PomBase Description
rRNA (guanine) methyltransferase Bud23 (predicted)


AspGD Description
Ortholog(s) have rRNA (guanine) methyltransferase activity


References

Bork P, et al. (1992 Dec). Comprehensive sequence analysis of the 182 predicted open reading frames of yeast chromosome III.

Niewmierzycka A, et al. (1999 Jan 8). S-Adenosylmethionine-dependent methylation in Saccharomyces cerevisiae. Identification of a novel protein arginine methyltransferase.

Ni L, et al. (2001 Jul). A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae.

Katz JE, et al. (2003 Aug). Automated identification of putative methyltransferases from genomic open reading frames.

White J, et al. (2008 May). Bud23 methylates G1575 of 18S rRNA and is required for efficient nuclear export of pre-40S subunits.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Lin JL, et al. (2012 Dec). New phenotypes generated by the G57R mutation of BUD23 in Saccharomyces cerevisiae.

Figaro S, et al. (2012 Jun). Trm112 is required for Bud23-mediated methylation of the 18S rRNA at position G1575.

Sardana R, et al. (2012 Nov). The methyltransferase adaptor protein Trm112 is involved in biogenesis of both ribosomal subunits.

Chen Z, et al. (2012 Oct). A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.

Sardana R, et al. (2013 Jun). The rRNA methyltransferase Bud23 shows functional interaction with components of the SSU processome and RNase MRP.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Sardana R, et al. (2014 Jun). Physical and functional interaction between the methyltransferase Bud23 and the essential DEAH-box RNA helicase Ecm16.

Zhang X, et al. (2015 Oct 9). Characterization of Tamoxifen as an Antifungal Agent Using the Yeast Schizosaccharomyces Pombe Model Organism.

Gaspa L, et al. (2016). A functional genome-wide genetic screening identifies new pathways controlling the G1/S transcriptional wave.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%