FOG11616
EOG8PNVXS

sce:TSC11

Genes: 31

SGD Description
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p); TORC2 is a membrane-associated complex that regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; involved in sphingolipid metabolism; contains a RasGEFN domain


PomBase Description
Rictor homolog, Ste20


AspGD Description
Ortholog(s) have TORC2 complex, cell division site, cytosol, nucleus localization


References

Loewith R, et al. (2002 Sep). Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.

Wedaman KP, et al. (2003 Mar). Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae.

Ho HL, et al. (2005 May). Saccharomyces cerevisiaeTSC11/AVO3 participates in regulating cell integrity and functionally interacts with components of the Tor2 complex.

Wullschleger S, et al. (2005 Sep 2). Molecular organization of target of rapamycin complex 2.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 26 genes with posterior transmembrane prediction > 50%