FOG11521
EOG8PVMKX

sce:MOT3

Genes: 3

SGD Description
Transcriptional repressor and activator with two C2-H2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth and ergosterol biosynthetic genes in response to hyperosmotic stress; contributes to recruitment of Tup1p-Cyc8p general repressor to promoters; involved in positive transcriptional regulation of CWP2 and other genes; relocalizes to the cytosol in response to hypoxia; can form [MOT3+] prion


References

Madison JM, et al. (1998 Apr). Identification and analysis of Mot3, a zinc finger protein that binds to the retrotransposon Ty long terminal repeat (delta) in Saccharomyces cerevisiae.

Grishin AV, et al. (1998 Jun). Mot3, a Zn finger transcription factor that modulates gene expression and attenuates mating pheromone signaling in Saccharomyces cerevisiae.

Kastaniotis AJ, et al. (2000 Oct). Roles of transcription factor Mot3 and chromatin in repression of the hypoxic gene ANB1 in yeast.

Hongay C, et al. (2002 Aug 1). Mot3 is a transcriptional repressor of ergosterol biosynthetic genes and is required for normal vacuolar function in Saccharomyces cerevisiae.

Sertil O, et al. (2003 Oct 15). Synergistic repression of anaerobic genes by Mot3 and Rox1 in Saccharomyces cerevisiae.

Klinkenberg LG, et al. (2005 Apr). Combinatorial repression of the hypoxic genes of Saccharomyces cerevisiae by DNA binding proteins Rox1 and Mot3.

Alberti S, et al. (2009 Apr 3). A systematic survey identifies prions and illuminates sequence features of prionogenic proteins.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%