FOG11424
EOG8Q576R

sce:CIK1;VIK1

Genes: 6

SGD Description
Kinesin-associated protein; required for both karyogamy and mitotic spindle organization, interacts stably and specifically with Kar3p and may function to target this kinesin to a specific cellular role; locus encodes a long and short transcript with differing functions; CIK1 has a paralog, VIK1, that arose from the whole genome duplication|Protein that forms a kinesin-14 heterodimeric motor with Kar3p; localizes Kar3p at mitotic spindle poles; has a structure similar to a kinesin motor domain but lacks an ATP-binding site and is catalytically inactive; binds microtubules; required for sister chromatid cohesion; VIK1 has a paralog, CIK1, that arose from the whole genome duplication


References

Page BD, et al. (1992 Aug). CIK1: a developmentally regulated spindle pole body-associated protein important for microtubule functions in Saccharomyces cerevisiae.

Manning BD, et al. (1999 Mar 22). Differential regulation of the Kar3p kinesin-related protein by two associated proteins, Cik1p and Vik1p.

Shanks RM, et al. (2001 Nov). The Kar3-interacting protein Cik1p plays a critical role in passage through meiosis I in Saccharomyces cerevisiae.

Duan D, et al. (2012 Nov 23). Neck rotation and neck mimic docking in the noncatalytic Kar3-associated protein Vik1.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%