FOG11412
EOG837Q1Z
EOG8Q5796

sce:ISA2

Genes: 34

SGD Description
Protein required for maturation of mitochondrial [4Fe-4S] proteins; functions in a complex with Isa1p and possibly Iba57p; localizes to the mitochondrial intermembrane space, overexpression of ISA2 suppresses grx5 mutations


PomBase Description
iron-sulfur cluster assembly protein Isa2


AspGD Description
Ortholog(s) have mitochondrion localization


References

Pelzer W, et al. (2000 Jul 7). Mitochondrial Isa2p plays a crucial role in the maturation of cellular iron-sulfur proteins.

Kim KD, et al. (2010 Feb 12). Monothiol glutaredoxin Grx5 interacts with Fe-S scaffold proteins Isa1 and Isa2 and supports Fe-S assembly and DNA integrity in mitochondria of fission yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%