FOG11348
EOG8QBZQM

sce:MRT4

Genes: 34

SGD Description
Protein involved in mRNA turnover and ribosome assembly; required at post-transcriptional step for efficient retrotransposition; localizes to the nucleolus


PomBase Description
mRNA turnover and ribosome assembly protein Mrt4 (predicted)


AspGD Description
Ortholog(s) have nucleolus localization


References

Zuk D, et al. (1999 Sep). Temperature-sensitive mutations in the Saccharomyces cerevisiae MRT4, GRC5, SLA2 and THS1 genes result in defects in mRNA turnover.

Harnpicharnchai P, et al. (2001 Sep). Composition and functional characterization of yeast 66S ribosome assembly intermediates.

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Rodríguez-Mateos M, et al. (2009 Dec). Role and dynamics of the ribosomal protein P0 and its related trans-acting factor Mrt4 during ribosome assembly in Saccharomyces cerevisiae.

Rodríguez-Mateos M, et al. (2009 Jun). The amino terminal domain from Mrt4 protein can functionally replace the RNA binding domain of the ribosomal P0 protein.

Lo KY, et al. (2009 Sep 21). Ribosome stalk assembly requires the dual-specificity phosphatase Yvh1 for the exchange of Mrt4 with P0.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Pan X, et al. (2012 Nov 23). Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library.

Chen JS, et al. (2013 May). Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Leidig C, et al. (2014 Mar 24). 60S ribosome biogenesis requires rotation of the 5S ribonucleoprotein particle.

Malecki M, et al. (2016 Nov 25). Functional and regulatory profiling of energy metabolism in fission yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%