FOG11332
EOG8QFTVH

sce:HO

Genes: 3

SGD Description
Site-specific endonuclease; required for gene conversion at the MAT locus (homothallic switching) through the generation of a ds DNA break; expression restricted to mother cells in late G1 as controlled by Swi4p-Swi6p, Swi5p, and Ash1p


References

Russell DW, et al. (1986 Dec). Structure of the Saccharomyces cerevisiae HO gene and analysis of its upstream regulatory region.

Herskowitz I, et al. (1991). Putting the HO gene to work: practical uses for mating-type switching.

Meiron H, et al. (1995 Sep). Identification of the heterothallic mutation in HO-endonuclease of S. cerevisiae using HO/ho chimeric genes.

Kaplun L, et al. (2000 Aug 29). Functions of the DNA damage response pathway target Ho endonuclease of yeast for degradation via the ubiquitin-26S proteasome system.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%