FOG11323
EOG8QFTWJ

sce:VPS36

Genes: 34

SGD Description
Component of the ESCRT-II complex; contains the GLUE (GRAM Like Ubiquitin binding in EAP45) domain which is involved in interactions with ESCRT-I and ubiquitin-dependent sorting of proteins into the endosome; plays a role in the formation of mutant huntingtin (Htt) aggregates in yeast


PomBase Description
ESCRT II complex subunit Vps36


AspGD Description
Ortholog(s) have ubiquitin binding activity


References

Babst M, et al. (2002 Aug). Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body.

Alam SL, et al. (2004 Apr 7). Ubiquitin interactions of NZF zinc fingers.

Teo H, et al. (2004 Oct). ESCRT-II, an endosome-associated complex required for protein sorting: crystal structure and interactions with ESCRT-III and membranes.

Hierro A, et al. (2004 Sep 9). Structure of the ESCRT-II endosomal trafficking complex.

Calcagno-Pizarelli AM, et al. (2011 Dec 1). Rescue of Aspergillus nidulans severely debilitating null mutations in ESCRT-0, I, II and III genes by inactivation of a salt-tolerance pathway allows examination of ESCRT gene roles in pH signalling.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%