FOG11185
EOG8QV9V0

sce:PEP7

Genes: 32

SGD Description
Adaptor protein involved in vesicle-mediated vacuolar protein sorting; multivalent adaptor protein; facilitates vesicle-mediated vacuolar protein sorting by ensuring high-fidelity vesicle docking and fusion, which are essential for targeting of vesicles to the endosome; required for vacuole inheritance


PomBase Description
prevacuole/endosomal FYVE tethering component Pep7 (predicted)


AspGD Description
Ortholog(s) have phosphatidylinositol-3-phosphate binding activity and role in Golgi to endosome transport, Golgi to vacuole transport, vacuole inheritance, vesicle docking involved in exocytosis, vesicle fusion


References

Weisman LS, et al. (1992 Jan 5). Molecular characterization of VAC1, a gene required for vacuole inheritance and vacuole protein sorting.

Webb GC, et al. (1997 May). Pep7p provides a novel protein that functions in vesicle-mediated transport between the yeast Golgi and endosome.

Tall GG, et al. (1999 Jun). The phosphatidylinositol 3-phosphate binding protein Vac1p interacts with a Rab GTPase and a Sec1p homologue to facilitate vesicle-mediated vacuolar protein sorting.

Srivastava A, et al. (2000 Sep). Pep3p/Pep5p complex: a putative docking factor at multiple steps of vesicular transport to the vacuole of Saccharomyces cerevisiae.

Galagan JE, et al. (2005 Dec 22). Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.

Abenza JF, et al. (2010 Aug 1). Aspergillus RabB Rab5 integrates acquisition of degradative identity with the long distance movement of early endosomes.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Sun LL, et al. (2013). Global analysis of fission yeast mating genes reveals new autophagy factors.

Rallis C, et al. (2014 Feb 15). Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%