FOG11103
EOG8R229F

sce:PTC6

Genes: 34

SGD Description
Mitochondrial type 2C protein phosphatase (PP2C); has similarity to mammalian PP1Ks; involved in mitophagy; null mutant is sensitive to rapamycin and has decreased phosphorylation of the Pda1 subunit of pyruvate dehydrogenase


PomBase Description
protein phosphatase 2C Ptc4


AspGD Description
Ortholog(s) have magnesium-dependent protein serine/threonine phosphatase activity


References

Tal R, et al. (2007 Feb 23). Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival.

Ruan H, et al. (2007 Mar). The YCR079w gene confers a rapamycin-resistant function and encodes the sixth type 2C protein phosphatase in Saccharomyces cerevisiae.

Gey U, et al. (2008 Apr 11). Yeast pyruvate dehydrogenase complex is regulated by a concerted activity of two kinases and two phosphatases.

Son S, et al. (2009 Apr). Analysis of all protein phosphatase genes in Aspergillus nidulans identifies a new mitotic regulator, fcp1.

de Assis LJ, et al. (2015 Mar 11). Multiple Phosphatases Regulate Carbon Source-Dependent Germination and Primary Metabolism in Aspergillus nidulans.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%