FOG10996
EOG8R7SZ4

sce:SSS1

Genes: 30

SGD Description
Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p); this complex forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p


PomBase Description
translocon gamma subunit Sss1 (predicted)


AspGD Description
Putative SEC61 complex subunit; expression enhanced by maltose; expression induced by tunicamycin and DTT


References

Esnault Y, et al. (1993 Nov). The yeast SSS1 gene is essential for secretory protein translocation and encodes a conserved protein of the endoplasmic reticulum.

Hanein D, et al. (1996 Nov 15). Oligomeric rings of the Sec61p complex induced by ligands required for protein translocation.

Hamman BD, et al. (1997 May 16). The aqueous pore through the translocon has a diameter of 40-60 A during cotranslational protein translocation at the ER membrane.

Johnson AE, et al. (1999). The translocon: a dynamic gateway at the ER membrane.

Prinz A, et al. (2000 Apr 17). Evolutionarily conserved binding of ribosomes to the translocation channel via the large ribosomal RNA.

Chavan M, et al. (2005 Jun 17). Subunits of the translocon interact with components of the oligosaccharyl transferase complex.

Sims AH, et al. (2005 May). Transcriptome analysis of recombinant protein secretion by Aspergillus nidulans and the unfolded-protein response in vivo.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 29 genes with posterior transmembrane prediction > 50%