FOG10930
EOG815DWD
EOG8RFJBC

sce:PFA4

Genes: 32

SGD Description
Palmitoyltransferase with autoacylation activity; required for palmitoylation of amino acid permeases containing a C-terminal Phe-Trp-Cys site; required for modification of Chs3p; member of the DHHC family of putative palmitoyltransferases


AspGD Description
Ortholog(s) have palmitoyltransferase activity, role in protein palmitoylation and endoplasmic reticulum localization


References

Zhao L, et al. (2002 Dec 20). Erf4p and Erf2p form an endoplasmic reticulum-associated complex involved in the plasma membrane localization of yeast Ras proteins.

Chibana H, et al. (2005 Aug). Sequence finishing and gene mapping for Candida albicans chromosome 7 and syntenic analysis against the Saccharomyces cerevisiae genome.

Valdez-Taubas J, et al. (2005 Jul 20). Swf1-dependent palmitoylation of the SNARE Tlg1 prevents its ubiquitination and degradation.

Smotrys JE, et al. (2005 Sep 26). The vacuolar DHHC-CRD protein Pfa3p is a protein acyltransferase for Vac8p.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Lam KK, et al. (2006 Jul 3). Palmitoylation by the DHHC protein Pfa4 regulates the ER exit of Chs3.

Roth AF, et al. (2006 Jun 2). Global analysis of protein palmitoylation in yeast.

González Montoro A, et al. (2015 Sep 11). The canonical DHHC motif is not absolutely required for the activity of the yeast S-acyltransferases Swf1 and Pfa4.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 32 genes with posterior transmembrane prediction > 50%