FOG05366
EOG831ZD3

sce:ARK1;PRK1

Genes: 36

SGD Description
Serine/threonine protein kinase; involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis; ARK1 has a paralog, PRK1, that arose from the whole genome duplication|Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex; PRK1 has a paralog, ARK1, that arose from the whole genome duplication


PomBase Description
Ark1/Prk1 family protein kinase Ppk29|Ark1/Prk1 family protein kinase Ppk30


AspGD Description
Ortholog(s) have protein serine/threonine kinase activity


References

Thiagalingam S, et al. (1995 Jun 20). PAK1, a gene that can regulate p53 activity in yeast.

Cope MJ, et al. (1999 Mar 22). Novel protein kinases Ark1p and Prk1p associate with and regulate the cortical actin cytoskeleton in budding yeast.

Zeng G, et al. (2001 Dec). Regulation of yeast actin cytoskeleton-regulatory complex Pan1p/Sla1p/End3p by serine/threonine kinase Prk1p.

Watson HA, et al. (2001 Nov). In vivo role for actin-regulating kinases in endocytosis and yeast epsin phosphorylation.

Fazi B, et al. (2002 Feb 15). Unusual binding properties of the SH3 domain of the yeast actin-binding protein Abp1: structural and functional analysis.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Blankenship JR, et al. (2010 Feb 5). An extensive circuitry for cell wall regulation in Candida albicans.

Shiroiwa Y, et al. (2011 Mar 21). Mis17 is a regulatory module of the Mis6-Mal2-Sim4 centromere complex that is required for the recruitment of CenH3/CENP-A in fission yeast.

Zeng G, et al. (2012 Sep). Cdc28-Cln3 phosphorylation of Sla1 regulates actin patch dynamics in different modes of fungal growth.

De Souza CP, et al. (2013). Functional analysis of the Aspergillus nidulans kinome.

Epp E, et al. (2013 Aug 27). Clathrin- and Arp2/3-independent endocytosis in the fungal pathogen Candida albicans.

Brown NA, et al. (2013 Jun 25). Functional characterisation of the non-essential protein kinases and phosphatases regulating Aspergillus nidulans hydrolytic enzyme production.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Guo Y, et al. (2014 Jul). Large scale screening of genetic interaction with sgf73(+) in fission yeast.

Swaffer MP, et al. (2016 Dec 15). CDK Substrate Phosphorylation and Ordering the Cell Cycle.

Larson A, et al. (2016 Jun 1). Interconnections Between RNA-Processing Pathways Revealed by a Sequencing-Based Genetic Screen for Pre-mRNA Splicing Mutants in Fission Yeast.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG05367
EOG831ZD3

sce:AKL1

Genes: 25

SGD Description
Ser-Thr protein kinase; member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization


References

Peng J, et al. (2003 Aug). A proteomics approach to understanding protein ubiquitination.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG05368
EOG831ZD3

sce:absent

Genes: 1

PomBase Description
Ark1/Prk1 family protein kinase Ppk38

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%