FOG05329
EOG841NTG

sce:OLA1

Genes: 34

SGD Description
P-loop ATPase with similarity to human OLA1 and bacterial YchF; identified as specifically interacting with the proteasome; null mutant displays increased translation rate and increased readthrough of premature stop codons; protein abundance increases in response to hydrogen peroxide and to DNA replication stress


PomBase Description
Obg-Like ATPase (predicted)


AspGD Description
Ortholog(s) have ATPase activity and cytosol, nucleus localization


References

Godon C, et al. (1998 Aug 28). The H2O2 stimulon in Saccharomyces cerevisiae.

Rout MP, et al. (2000 Feb 21). The yeast nuclear pore complex: composition, architecture, and transport mechanism.

Guerrero C, et al. (2006 Feb). An integrated mass spectrometry-based proteomic approach: quantitative analysis of tandem affinity-purified in vivo cross-linked protein complexes (QTAX) to decipher the 26 S proteasome-interacting network.

Koller-Eichhorn R, et al. (2007 Jul 6). Human OLA1 defines an ATPase subfamily in the Obg family of GTP-binding proteins.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Tkach JM, et al. (2012 Sep). Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG05330
EOG841NTG

sce:YLF2

Genes: 21

SGD Description
Protein of unknown function; has weak similarity to E. coli GTP-binding protein gtp1; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies


References

Hermann-Le Denmat S, et al. (1994 Jul 1). Suppression of yeast RNA polymerase III mutations by the URP2 gene encoding a protein homologous to the mammalian ribosomal protein S20.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG05331
EOG841NTG

sce:absent

Genes: 4

PomBase Description
mitochondrial NTPase Ylf2 (predicted)

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%