FOG05236
EOG86DJM4
EOG8NK9H9
sce:CIN5
Genes: 12
SGD DescriptionBasic leucine zipper (bZIP) transcription factor of the yAP-1 family; physically interacts with the Tup1-Cyc8 complex and recruits Tup1p to its targets; mediates pleiotropic drug resistance and salt tolerance; nuclearly localized under oxidative stress and sequestered in the cytoplasm by Lot6p under reducing conditions; CIN5 has a paralog, YAP6, that arose from the whole genome duplication
References
Fernandes L, et al. (1997 Dec). Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions.
Mendizabal I, et al. (1998 Mar 27). Yeast putative transcription factors involved in salt tolerance.
Delling U, et al. (1998 May). Identification of Saccharomyces cerevisiae genes conferring resistance to quinoline ring-containing antimalarial drugs.
Furuchi T, et al. (2001 Mar). Two nuclear proteins, Cin5 and Ydr259c, confer resistance to cisplatin in Saccharomyces cerevisiae.
Lee TI, et al. (2002 Oct 25). Transcriptional regulatory networks in Saccharomyces cerevisiae.
Bar-Joseph Z, et al. (2003 Nov). Computational discovery of gene modules and regulatory networks.
Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.