FOG05233
EOG86Q57G

sce:SAP155;SAP4;SAP185;SAP190

Genes: 41

SGD Description
Protein required for function of the Sit4p protein phosphatase; forms a complex with Sit4p; member of a family of similar proteins including Sap4p, Sap185p, and Sap190p; protein abundance increases in response to DNA replication stress; SAP155 has a paralog, SAP4, that arose from the whole genome duplication|Protein required for function of the Sit4p protein phosphatase; member of a family of similar proteins that form complexes with Sit4p, including Sap155p, Sap185p, and Sap190p; SAP4 has a paralog, SAP155, that arose from the whole genome duplication|Protein that forms a complex with the Sit4p protein phosphatase; required for Sit4p function; member of a family of similar proteins including Sap4p, Sap155p, and Sap190p; SAP185 has a paralog, SAP190, that arose from the whole genome duplication|Protein that forms a complex with the Sit4p protein phosphatase; required for Sit4p function; member of a family of similar proteins including Sap4p, Sap155p, and Sap185p; SAP190 has a paralog, SAP185, that arose from the whole genome duplication


PomBase Description
protein phosphatase regulatory subunit Ekc1 (predicted)


AspGD Description
Ortholog(s) have role in G1/S transition of mitotic cell cycle, regulation of mitotic sister chromatid segregation, tRNA wobble uridine modification and cytosol, mitochondrion, nuclear pericentric heterochromatin localization


References

Luke MM, et al. (1996 Jun). The SAP, a new family of proteins, associate and function positively with the SIT4 phosphatase.

Jablonowski D, et al. (2001 Dec). Sit4p protein phosphatase is required for sensitivity of Saccharomyces cerevisiae to Kluyveromyces lactis zymocin.

Goshima G, et al. (2003 Jun 2). The role of Ppe1/PP6 phosphatase for equal chromosome segregation in fission yeast kinetochore.

Jablonowski D, et al. (2004 Mar). The yeast elongator histone acetylase requires Sit4-dependent dephosphorylation for toxin-target capacity.

Rohde JR, et al. (2004 Oct). TOR controls transcriptional and translational programs via Sap-Sit4 protein phosphatase signaling effectors.

Manlandro CM, et al. (2005 Jun). Ability of Sit4p to promote K+ efflux via Nha1p is modulated by Sap155p and Sap185p.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Hanyu Y, et al. (2009 May). Schizosaccharomyces pombe cell division cycle under limited glucose requires Ssp1 kinase, the putative CaMKK, and Sds23, a PP2A-related phosphatase inhibitor.

Takeda K, et al. (2011). Identification of genes affecting the toxicity of anti-cancer drug bortezomib by genome-wide screening in S. pombe.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Wang J, et al. (2013 Sep 1). Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Malecki M, et al. (2016). Identifying genes required for respiratory growth of fission yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG05234
EOG86Q57G

sce:absent

Genes: 14

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%