FOG05219
EOG873N9G

sce:NAT3

Genes: 32

SGD Description
Catalytic subunit of the NatB N-terminal acetyltransferase; NatB catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met


PomBase Description
NatB N-acetyltransferase complex catalytic subunit Naa20 (predicted)


AspGD Description
Ortholog(s) have peptide alpha-N-acetyltransferase activity, role in N-terminal peptidyl-methionine acetylation, mitochondrion inheritance, regulation of actin cytoskeleton organization and NatB complex, cytosol, nucleus localization


References

Polevoda B, et al. (1999 Nov 1). Identification and specificities of N-terminal acetyltransferases from Saccharomyces cerevisiae.

Polevoda B, et al. (2003 Aug 15). Nat3p and Mdm20p are required for function of yeast NatB Nalpha-terminal acetyltransferase and of actin and tropomyosin.

Singer JM, et al. (2003 Jun 24). Mdm20 protein functions with Nat3 protein to acetylate Tpm1 protein and regulate tropomyosin-actin interactions in budding yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Malecki M, et al. (2016 Nov 25). Functional and regulatory profiling of energy metabolism in fission yeast.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Hong H, et al. (2017 Apr 4). Molecular Basis of Substrate Specific Acetylation by N-Terminal Acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG05220
EOG873N9G

sce:ARD1

Genes: 32

SGD Description
Subunit of protein N-terminal acetyltransferase NatA; NatA is comprised of Nat1p, Ard1p, and Nat5p; acetylates many proteins and thus affects telomeric silencing, cell cycle, heat-shock resistance, mating, and sporulation; human Ard1p levels are elevated in cancer cells; protein abundance increases in response to DNA replication stress


PomBase Description
NatA N-acetyltransferase complex catalytic subunit Naa10 (predicted)


AspGD Description
Ortholog(s) have peptide alpha-N-acetyltransferase activity, peptide-glutamate-N-acetyltransferase activity, peptide-serine-N-acetyltransferase activity


References

Whiteway M, et al. (1985 Dec). The ARD1 gene of yeast functions in the switch between the mitotic cell cycle and alternative developmental pathways.

Mullen JR, et al. (1989 Jul). Identification and characterization of genes and mutants for an N-terminal acetyltransferase from yeast.

Park EC, et al. (1992 Jun). ARD1 and NAT1 proteins form a complex that has N-terminal acetyltransferase activity.

Gautschi M, et al. (2003 Oct). The yeast N(alpha)-acetyltransferase NatA is quantitatively anchored to the ribosome and interacts with nascent polypeptides.

Nützmann HW, et al. (2011 Aug 23). Bacteria-induced natural product formation in the fungus Aspergillus nidulans requires Saga/Ada-mediated histone acetylation.

Banerjee S, et al. (2013 Aug). Splicing functions and global dependency on fission yeast slu7 reveal diversity in spliceosome assembly.

Liszczak G, et al. (2013 Sep). Molecular basis for N-terminal acetylation by the heterodimeric NatA complex.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG05221
EOG873N9G

sce:absent

Genes: 1

AspGD Description
Has domain(s) with predicted N-acetyltransferase activity

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%