FOG05144
EOG88W9JN

sce:RAD4

Genes: 33

SGD Description
Protein that recognizes and binds damaged DNA (with Rad23p) during NER; subunit of Nuclear Excision Repair Factor 2 (NEF2); also involved, with Rad23p, in turnover of ubiquitylated proteins; NER stands for nucleotide excision repair


PomBase Description
DNA repair protein Rhp41


AspGD Description
Ortholog(s) have role in mismatch repair, nucleotide-excision repair and mitotic spindle, nucleus localization


References

Gietz RD, et al. (1988 Dec 30). Cloning and nucleotide sequence analysis of the Saccharomyces cerevisiae RAD4 gene required for excision repair of UV-damaged DNA.

Couto LB, et al. (1989 Apr). Nucleotide sequence of the wild-type RAD4 gene of Saccharomyces cerevisiae and characterization of mutant rad4 alleles.

Fukumoto Y, et al. (2002 Oct 1). Two budding yeast RAD4 homologs in fission yeast play different roles in the repair of UV-induced DNA damage.

Marti TM, et al. (2003 Jun). Repair of damaged and mismatched DNA by the XPC homologues Rhp41 and Rhp42 of fission yeast.

Lee KM, et al. (2007 Apr). Brc1-mediated rescue of Smc5/6 deficiency: requirement for multiple nucleases and a novel Rad18 function.

Dixon SJ, et al. (2008 Oct 28). Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes.

Deshpande GP, et al. (2009 May 1). Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance.

Han TX, et al. (2010). Global fitness profiling of fission yeast deletion strains by barcode sequencing.

Kanamitsu K, et al. (2011). Fission yeast homologs of human XPC and CSB, rhp41 and rhp26, are involved in transcription-coupled repair of methyl methanesulfonate-induced DNA damage.

Buttrick GJ, et al. (2011 Dec). Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B.

Arita Y, et al. (2011 May). Microarray-based target identification using drug hypersensitive fission yeast expressing ORFeome.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Chen Z, et al. (2012 Oct). A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.

Guo Y, et al. (2014 Jul). Large scale screening of genetic interaction with sgf73(+) in fission yeast.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 7 genes with posterior transmembrane prediction > 50%

FOG05145
EOG88W9JN

sce:RAD34

Genes: 10

SGD Description
Protein involved in nucleotide excision repair (NER); homologous to RAD4


References

den Dulk B, et al. (2005 Jun). The Rad4 homologue YDR314C is essential for strand-specific repair of RNA polymerase I-transcribed rDNA in Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 5 genes with posterior transmembrane prediction > 50%

FOG05146
EOG88W9JN

sce:absent

Genes: 6

PomBase Description
DNA repair protein Rhp42


AspGD Description
Ortholog(s) have role in mismatch repair, nucleotide-excision repair and nucleolus localization


References

Fukumoto Y, et al. (2002 Oct 1). Two budding yeast RAD4 homologs in fission yeast play different roles in the repair of UV-induced DNA damage.

Marti TM, et al. (2003 Jun). Repair of damaged and mismatched DNA by the XPC homologues Rhp41 and Rhp42 of fission yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%