FOG05109
EOG89KDBK

sce:COA3

Genes: 27

SGD Description
Mitochondrial protein required for cytochrome c oxidase assembly; also involved in translational regulation of Cox1p and prevention of Cox1p aggregation before assembly; located in the mitochondrial inner membrane


PomBase Description
cytochrome C oxidase assembly factor 3, Coa3 (predicted)


AspGD Description
Ortholog of A. nidulans FGSC A4 : AN11304, Neosartorya fischeri NRRL 181 : NFIA_097160, Aspergillus wentii : Aspwe1_0043859 and Aspergillus versicolor : Aspve1_0079468


References

Blandin G, et al. (2000 Dec 22). Genomic exploration of the hemiascomycetous yeasts: 4. The genome of Saccharomyces cerevisiae revisited.

Reinders J, et al. (2006 Jul). Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Kastenmayer JP, et al. (2006 Mar). Functional genomics of genes with small open reading frames (sORFs) in S. cerevisiae.

Merz S, et al. (2009). Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae.

Mick DU, et al. (2010 Oct 4). Coa3 and Cox14 are essential for negative feedback regulation of COX1 translation in mitochondria.

Fontanesi F, et al. (2011 Jan 7). Cox25 teams up with Mss51, Ssc1, and Cox14 to regulate mitochondrial cytochrome c oxidase subunit 1 expression and assembly in Saccharomyces cerevisiae.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 26 genes with posterior transmembrane prediction > 50%