FOG05084
EOG8B5MSH

sce:RSC8

Genes: 34

SGD Description
Component of the RSC chromatin remodeling complex; essential for viability and mitotic growth; homolog of SWI/SNF subunit Swi3p, but unlike Swi3p, does not activate transcription of reporters


PomBase Description
SWI/SNF and RSC complex subunit Ssr2


AspGD Description
Ortholog(s) have RSC complex, SWI/SNF complex, cytoplasm localization


References

Cairns BR, et al. (1996 Dec 27). RSC, an essential, abundant chromatin-remodeling complex.

Treich I, et al. (1997 Apr). Interaction of a Swi3 homolog with Sth1 provides evidence for a Swi/Snf-related complex with an essential function in Saccharomyces cerevisiae.

Treich I, et al. (1998 Aug 15). Direct interaction between Rsc6 and Rsc8/Swh3,two proteins that are conserved in SWI/SNF-related complexes.

Lorch Y, et al. (1999 Feb 5). Histone octamer transfer by a chromatin-remodeling complex.

Moreira JM, et al. (1999 May 17). Transcriptional repression of the yeast CHA1 gene requires the chromatin-remodeling complex RSC.

Cairns BR, et al. (1999 Nov). Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains.

Saha A, et al. (2002 Aug 15). Chromatin remodeling by RSC involves ATP-dependent DNA translocation.

Chai B, et al. (2002 Jun). Yeast RSC function is required for organization of the cellular cytoskeleton via an alternative PKC1 pathway.

Boyer LA, et al. (2002 Oct). Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes.

Lu YM, et al. (2003 Jun). Dissecting the pet18 mutation in Saccharomyces cerevisiae: HTL1 encodes a 7-kDa polypeptide that interacts with components of the RSC complex.

Hsu JM, et al. (2003 May). The yeast RSC chromatin-remodeling complex is required for kinetochore function in chromosome segregation.

Wilson B, et al. (2006 Feb). The RSC chromatin remodeling complex bears an essential fungal-specific protein module with broad functional roles.

Monahan BJ, et al. (2008 Aug). Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.

Wang J, et al. (2013 Sep 1). Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG05085
EOG8B5MSH

sce:SWI3

Genes: 26

SGD Description
Subunit of the SWI/SNF chromatin remodeling complex; SWI/SNF regulates transcription by remodeling chromosomes; contains SANT domain that is required for SWI/SNF assembly; is essential for displacement of histone H2A-H2B dimers during ATP-dependent remodeling; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; relocates to the cytosol under hypoxic conditions


References

Peterson CL, et al. (1992 Feb 7). Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription.

Löhning C, et al. (1993 Sep). Isolation of the TYE2 gene reveals its identity to SWI3 encoding a general transcription factor in Saccharomyces cerevisiae.

Smith CL, et al. (2003 Feb). Structural analysis of the yeast SWI/SNF chromatin remodeling complex.

Lee KK, et al. (2004 Dec). Proteomic analysis of chromatin-modifying complexes in Saccharomyces cerevisiae identifies novel subunits.

Wilson B, et al. (2006 Feb). The RSC chromatin remodeling complex bears an essential fungal-specific protein module with broad functional roles.

Da G, et al. (2006 Feb 14). Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG05086
EOG8B5MSH

sce:absent

Genes: 1

PomBase Description
SWI/SNF and RSC complex subunit Ssr1


References

Monahan BJ, et al. (2008 Aug). Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Nie M, et al. (2015 Sep 25). High Confidence Fission Yeast SUMO Conjugates Identified by Tandem Denaturing Affinity Purification.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%