FOG05049
EOG8BZKNJ
sce:TOA1
Genes: 30
SGD DescriptionTFIIA large subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; required, along with Toa2p, for ribosomal protein gene transcription in vivo; homologous to largest and second largest subunits of human and Drosophila TFIIA
PomBase Descriptiontranscription factor TFIIA complex large subunit Toa1 (predicted)
AspGD DescriptionOrtholog(s) have RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly, TBP-class protein binding activity
References
Ranish JA, et al. (1992 Feb 28). Isolation of two genes that encode subunits of the yeast transcription factor IIA.
Tan S, et al. (1996 May 9). Crystal structure of a yeast TFIIA/TBP/DNA complex.
Titov AA, et al. (1999 Oct 18). The karyopherin Kap122p/Pdr6p imports both subunits of the transcription factor IIA into the nucleus.
Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.
Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.