FOG05049
EOG8BZKNJ

sce:TOA1

Genes: 30

SGD Description
TFIIA large subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; required, along with Toa2p, for ribosomal protein gene transcription in vivo; homologous to largest and second largest subunits of human and Drosophila TFIIA


PomBase Description
transcription factor TFIIA complex large subunit Toa1 (predicted)


AspGD Description
Ortholog(s) have RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly, TBP-class protein binding activity


References

Ranish JA, et al. (1992 Feb 28). Isolation of two genes that encode subunits of the yeast transcription factor IIA.

Tan S, et al. (1996 May 9). Crystal structure of a yeast TFIIA/TBP/DNA complex.

Titov AA, et al. (1999 Oct 18). The karyopherin Kap122p/Pdr6p imports both subunits of the transcription factor IIA into the nucleus.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%